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The studies available are small, largely uncontrolled, and not sufficient to draw conclusions about efficacy or safety in humans

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According to data from the Cochrane review, administration of carnitines and combined AOX formulations had positive effect of sperm motility, and supplementation with polyunsaturated fats and zinc resulted in increase of sperm concentration ( Sperm recovery in patients with non-obstructive azoospermia A study investigated the outcome of three-month supplementation with multivitamins, micronutrients and CoQ10 in infertile men with non-obstructive azoospermia (n=24) as compared to no treatment (n=11) (104)